The Man with Two Brains

Steve Martin

Dr. Michael Hfuhruhurr

Kathleen Turner

Dolores Benedict

David Warner

Dr. Alfred Necessiter

Paul Benedict

Butler

Richard Brestoff

Dr. Pasteur

James Cromwell

Realtor

George Furth

Timon

Peter Hobbs

Dr. Brandon

Earl Boen

Dr. Felix Conrad

Bernie Hern

Gun Seller

Francis X. McCarthy

Olsen

William Traylor

Inspector

Randi Brooks

Fran

Bernard Behrens

James Gladstone

Natividad Vacío

Ramon

David Byrd

Desk Clerk

Adrian Ricard

Nurse in Room

Sparky Marcus

Bellboy

Perla Walter

Housekeeper

Mya Stark

Little Girl

Don McLeod

Dr. Schlermie Beckerman / Gorilla

Peter Elbling

Morgue Attendant

Kate Sarchet

Hooker #2

Wendy Sherman

Hooker #3

Tom Spratley

Minister

Estelle Reiner

Tourist in Elevator

Jeffrey Combs

Dr. Jones

Jenny Gago

Nurse #1

Haunani Minn

Nurse Breen

Stepfanie Kramer

Beautiful Girl Hit by Car

George Fisher

Patrol Car Officer

Merv Griffin

The Elevator Killer

Bob Harks

Lecture Guest (uncredited)

Sissy Spacek

Anne Uumellmahaye (uncredited) (voice)